According to the material, which type of medication is discouraged in fibromyalgia?

According to the material, which type of medication is discouraged in fibromyalgia?

• A. Antidepressants
• B. NSAIDs
• C. Pregabalin
• D. Cyclobenzaprine

Answer: (B)

Fibromyalgia pain is driven more by altered central pain processing than by tissue inflammation. NSAIDs target inflammation and peripheral pain signals, so they often provide little relief for fibromyalgia symptoms. Because the underlying issue is centralized pain amplification, treatments that modulate the nervous system’s pain signaling—such as certain antidepressants and anticonvulsants like pregabalin, along with sleep-focused therapies—are preferred. Cyclobenzaprine can help sleep and muscle discomfort for some patients, but it’s not the main approach. For that reason, NSAIDs are discouraged as a primary treatment in fibromyalgia.

Fibromyalgia pain is driven more by altered central pain processing than by tissue inflammation. NSAIDs target inflammation and peripheral pain signals, so they often provide little relief for fibromyalgia symptoms. Because the underlying issue is centralized pain amplification, treatments that modulate the nervous system’s pain signaling—such as certain antidepressants and anticonvulsants like pregabalin, along with sleep-focused therapies—are preferred. Cyclobenzaprine can help sleep and muscle discomfort for some patients, but it’s not the main approach. For that reason, NSAIDs are discouraged as a primary treatment in fibromyalgia.